Formulation Development And Evaluation Of Effervescent Floating Matrix Tablet As Gastroretentive Drug Delivery System

 Pravin Babarao Suruse, Umesh Dhaniram Shivhare, Mrunalini Raghunath Raut

The present work was aim to formulate effervescent floating matrix tablets of Pentoxifylline as gastro retentive drug delivery system. Rapid gastrointestinal transit could result in incomplete drug release from the drug delivery system above the absorption zone leading to diminished efficacy of the administered dose. Pentoxifylline is the hemorrheologic agent, lowering blood viscosity and improving erythrocyte flexibility.

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